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GATE, a Geant4-based simulation platform for PET integrating movement and time management
Authore(s) : G. Santina || researche
Volume : (3), Issue : 211, February - 2019
Abstract : the Geant4 Application for Tomographic Emission, is a simulation platform developed for PET and SPECT. It combines a powerful simulation core (the Geant4 toolkit) and a large range of developments dedicated to nuclear medicine. In particular, it models the passing of time during real acquisitions, allowing to handle dynamic systems such as decaying source distributions or moving detectors. We present several series of results that illustrate the possibilities of this new platform. The simulation of decaying sources is illustrated on a dual-isotope acquisition with multiple time-frames. Count rate curves taking into account random coincidences and dead-time are shown for a dual-crystal set-up and for a small-animal PET scanner configuration. Simulated resolution curves and reconstructed images are shown for rotating PET scanners. Lastly, we present comparisons of simulated point-spread functions and spectra with experimental results obtained from a small-animal gamma camera prototype.
Keywords :PET and SPECT applications that include scanner design, statistical image reconstruction, scatter correction, protocol optimization
Article: Download PDF Journal DOI : 2364/2018
Cite This Article:
PET integrating movement and time management
Vol.I (3), Issue.I 211
Article No : 1067
Number of Downloads : 100
References :
Buvat and I. Castiglioni, “Monte Carlo simulations in SPET and PET,” Quaterly J. of Nucl. Med. 2002;46:48-61
GEANT4 Collaboration, “GEANT4: A simulation toolkit,” SLAC Report SLAC-PUB-9350, Aug. 2002
S. R. Cherry, Y. Shao, R. W. Silverman, K. Meadors, S. Siegel, A. Chatziioannou et al., “MicroPET: a high resolution PET scanner for imaging small animals,” IEEE Trans. Nucl. Sci 1997;44:1161-1166
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- Buvat and I. Castiglioni, “Monte Carlo simulations in SPET and PET,” Quaterly J. of Nucl. Med. 2002;46:48-61
- GEANT4 Collaboration, “GEANT4: A simulation toolkit,” SLAC Report SLAC-PUB-9350, Aug. 2002
- S. R. Cherry, Y. Shao, R. W. Silverman, K. Meadors, S. Siegel, A. Chatziioannou et al., “MicroPET: a high resolution PET scanner for imaging small animals,” IEEE Trans. Nucl. Sci 1997;44:1161-1166
- http://stir.irsl.org
- A. F. Chatziioannou, S. R. Cherry, Y. Shao, R. W. Silverman, K. Meadors, T. H. Farquhar et al., “Performance evaluation of microPET: a high-resolution lutetium oxyorthosilicate PET scanne for animal imaging,” J. of Nucl. Med. 1999;40:1164-1175
- G. K. Loudos, K. S. Nikita, N. D. Giokaris, E. Styliaris, S. C. Archimandritis, D. Varvarigou et al., “A 3D high-resolution gamma camera for radiopharmaceutical studies with small animals,” to be submitted
- http://www-iphe.unil.ch/~PET/research/gate/
... Less
- Buvat and I. Castiglioni, “Monte Carlo simulations in SPET and PET,” Quaterly J. of Nucl. Med. 2002;46:48-61
- GEANT4 Collaboration, “GEANT4: A simulation toolkit,” SLAC Report SLAC-PUB-9350, Aug. 2002
- S. R. Cherry, Y. Shao, R. W. Silverman, K. Meadors, S. Siegel, A. Chatziioannou et al., “MicroPET: a high resolution PET scanner for imaging small animals,” IEEE Trans. Nucl. Sci 1997;44:1161-1166
- http://stir.irsl.org
- A. F. Chatziioannou, S. R. Cherry, Y. Shao, R. W. Silverman, K. Meadors, T. H. Farquhar et al., “Performance evaluation of microPET: a high-resolution lutetium oxyorthosilicate PET scanne for animal imaging,” J. of Nucl. Med. 1999;40:1164-1175
- G. K. Loudos, K. S. Nikita, N. D. Giokaris, E. Styliaris, S. C. Archimandritis, D. Varvarigou et al., “A 3D high-resolution gamma camera for radiopharmaceutical studies with small animals,” to be submitted
- http://www-iphe.unil.ch/~PET/research/gate/